Servier CDMO Expands Preparative Chromatography Platform At Normandy Site To Support Market Need

The benefit is the speeding up of clinical supply and subsequent manufacture of complex molecules for medicines at commercial scale.

PARISOct. 19, 2017 /PRNewswire/ — Servier CDMO, the contract development and manufacturing organization (CDMO) division of Servier, today announced that the company has invested $7.5 million USD in intensified technology including continuous chromatography with simulated moving bed (SMB) and super critical fluid chromatography (SFC) with solvent recycling of up to 90% to lower environmental impact.

Servier CDMO expects at least a 50% increase in productivity in addition to the existing configuration of the high-volume batch columns that are used to manufacture drug substances. The investment will allow the chemical purification of 50kg (kilograms) per day, and the chiral separation of 10kg per day to support clinical trials and market supply upon drug approvals.

The highly qualified team at the Bolbec site, in Normandy, is composed of experts in chemical processes and is certified to handle highly potent compounds to occupational exposure band five (OEB 5). Bolbec is a fully United States Food & Drug Administration (FDA) current good manufacturing practice (cGMP) site for human pharmaceuticals.

Servier CDMO believes that this exceptional expertise and technology give pharmaceutical companies access to the means to accelerate the development and commercialization of novel therapies that will meet significant unmet patient needs for highly potent compounds.

About Servier CDMO

In 2015, Servier embarked on an initiative that would offer the company's highly-developed operations, quality culture and global drug and supply chain development skill set, ranging from complete manufacturing operations to the supply of discrete research and processing tasks (from starting materials and clinical trial batches to finished products), as outsource services in a contract services division, Servier CDMO, with manufacturing and research network of 11 facilities around the world that supplies even the most challenged markets and patient populations.

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For further information:
Gwenaël Servant, Ph.D.
Managing Director, Servier CDMO
Tel: +33 1 55 72 70 00


Nice Insight

Nice Insight, established in 2010, is the research division of That’s Nice, A Science Agency, providing data and analysis from proprietary annual surveys, custom primary qualitative and quantitative research as well as extensive secondary research. Current annual surveys include The Nice Insight Contract Development & Manufacturing (CDMO/CMO), Survey The Nice Insight Contract Research - Preclinical and Clinical (CRO) Survey, The Nice Insight Pharmaceutical Equipment Survey, and The Nice Insight Pharmaceutical Excipients Survey.


Servier is an international pharmaceutical company governed by a non-profit foundation, with its headquarters in France (Suresnes). With a strong international presence in 148 countries and a turnover of 4 billion euros in 2016, Servier employs 21 000 people worldwide. Entirely independent, the Group reinvests 25% of its turnover (excluding generic drugs) in research and development and uses all its profits for development. Corporate growth is driven by Servier's constant search for innovation in five areas of excellence: cardiovascular, immune-inflammatory and neuropsychiatric diseases, cancers and diabetes, as well as by its activities in high-quality generic drugs. More information: