Innovating Cell Therapy Manufacturing

At a Dublin, Ireland stop on the Road to 2021 trans-European road trip, Gary McAuslan, Founder and CEO of aCGT Vector, discusses the company’s plans to advance cell therapy manufacturing and why they selected Dublin to build the business.

Nice Insight

Nice Insight, established in 2010, is the research division of That’s Nice, A Science Agency, providing data and analysis from proprietary annual surveys, custom primary qualitative and quantitative research as well as extensive secondary research. Current annual surveys include The Nice Insight Contract Development & Manufacturing (CDMO/CMO), Survey The Nice Insight Contract Research - Preclinical and Clinical (CRO) Survey, The Nice Insight Pharmaceutical Equipment Survey, and The Nice Insight Pharmaceutical Excipients Survey.

aCGT Vector

aCGT Vector are a “Point of Care” Cellular Therapy Company, delivering precision medicines across a multiple hospital-based ATMP (Advanced Therapy Medicinal Product) GMP licensed facility network.  The leading Cell Therapy is CAR-T treatment, increasingly approved for reimbursement. 

Through its novel approach to integrate and digitally twin patient and PODular “GMP-in-a-POD” distributed manufacturing, it is rolling out across Cancer Centres of Excellence. Commencing in 2021 with its new facility in St. James’s Hospital in Dublin, this is a centre where almost 200 Bone Marrow transplant Cellular procedures take place annually.

aCGT Vector will offer Cell Therapy innovators’ accessible agile, right-sized manufacturing and clinical trial capacity across its network of POD’s. This will allow clinical trials to scale from N=1 (10-20 patient trial) to multiples of N=1 (>20 patient trials) across its multi-POD-centred clinical trials as therapies move along the clinical continuum.

Our ultimate goal is to make cancer history; by increasing accessibility to potentially curative personalised medicines, transforming lives of cancer patients, by giving consultants localised treatment options, and ultimately facilitate a paradigm shift towards distributed end-to-end point-of-care healthcare provision.

We are adapting our PODular approach to bring to market an end to end mRNA and DNA vaccine manufacturing platform using Touchlight’s dbDNA and Cytiva’s Single-use closed system FlexFactory mRNA, LNP to Vanrx fill finish technology within Ireland for broader PODular application across the EU.

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