Quentis Therapeutics is a preclinical stage biotechnology company that is translating novel biology into new therapeutic approaches that target pathways associated with endoplasmic reticulum (ER) stress response. The company's lead program is a first-in-class IRE1α inhibitor designed to boost anti-tumor immunity in cancer. Quentis is pursuing therapies to address multiple ER stress pathway targets in the tumor micro-environment, as well as in other diseases where ER stress plays an important role. New York City-based Quentis launched in February 2018 with the completion of a $48 million Series A financing which was co-led by founding investor Versant Ventures and Polaris Partners and the affiliated LS Polaris Innovation Fund.