Neutrolis is a biotechnology company developing first-in-class therapies that target neutrophils and their pathogenic products, including NETs. Neutrolis' proprietary platform, Chromatinase™, is based on the naturally occurring enzymes that break down the extracellular chromatin that form NETs. The company's lead product, NTR-441, is a patented, first-in-class, engineered DNASE1L3 analog with potential application in COVID-19, ARDS, lupus, rheumatoid arthritis, systemic sclerosis and other NET-mediated diseases. Neutrolis has received two competitive LabCentral Golden Ticket awards from Pfizer and Bristol-Myers Squibb. The company is privately held and has been supported to date by First Rice Capital and Prefix Capital, as well as individual investors and funding from the National Institutes of Health. It was founded by Drs. Toby Fox and Abdul Hakkim, two of the earliest and most cited leaders in the NETs field.