Berkeley Lights and TPG Biologics Enter into a Strategic Collaboration for Cell Line Development

Program Implements Beacon Platform for Creating Workflow Efficiencies to Accelerate the Drug Development Process

EMERYVILLE, Calif., May 23, 2018 /PRNewswire/ -- Berkeley Lights, Inc. (BLI), a leader in digital cell biology, announced today a program with Taipei-based TPG Biologics, Inc. (TPG), a leading cell line development company in Asia, focused on using the Beacon® optofluidic platform to accelerate TPG's cell line development workflow. The program includes identifying the top producing clones, evaluating and predicting the stability of the clones over multiple generations, and validating monoclonality. 

"TPG has already developed a streamlined cell line generation platform and generated dozens of production clones for our customers. We are always working to integrate innovative technologies to optimize our workflow. We chose to work with Berkeley Lights because the Beacon platform cell line development program has the potential to generate high yield cell lines more efficiently for us with additional insights into clone stability and enhanced clonality," said Pei-Jiun Chen, Ph.D., Chairman & President at TPG.

Clone stability is a critical requirement for cell line development. The Beacon platform is capable of screening thousands of clones in just five days. Different from traditional clone stability measurement that is based on measuring the productivity of a clone as a population, the Beacon platform is capable of evaluating a large number of subclones at a monocellular level in parallel.  Automating the process on the Beacon platform increases efficiencies and reduces overall costs as well as provides additional insights into the behavior of clonal populations that are not currently available using traditional techniques. 

"We are committed to delivering versatile platforms to our customers that can transform their workflows, generating time and cost savings," said Andy Last, Chief Commercial Officer at Berkeley Lights, Inc. "We look forward to working with TPG to support their goal of reaching a new level of scalability and precision that is unattainable with manual and semi-automated methods. TPG is located in Taipei and this strategic collaboration marks another significant step in BLI's expansion within Asia Pacific."


About TPG Biologics, Inc. (TPG)

TPG Biologics is a biotechnology company that specializes in the early stage research and development of biologics. As a Contract Research Organization (CRO), we provide reliable services for protein/antibody optimization, cell line development, process development, and analytics. From gene to RCB to process development and analytics, our workflow ensure that our clones have high productivities and good quality. In addition to TPG's CRO services, we offer a library of ready-to-ship cell clones expressing blockbuster antibody and protein biosimilars.


Nice Insight

Nice Insight, established in 2010, is the research division of That’s Nice, A Science Agency, providing data and analysis from proprietary annual surveys, custom primary qualitative and quantitative research as well as extensive secondary research. Current annual surveys include The Nice Insight Contract Development & Manufacturing (CDMO/CMO), Survey The Nice Insight Contract Research - Preclinical and Clinical (CRO) Survey, The Nice Insight Pharmaceutical Equipment Survey, and The Nice Insight Pharmaceutical Excipients Survey.

Berkeley Lights

‪Berkeley Lights, Inc. (BLI) Berkeley Lights is a digital cell biology company that develops and commercializes platforms for the acceleration of discovery, development, and delivery of cell based products and therapies.
At the intersection of biology, technology and information, our platforms automate the manipulation, analysis and selection of individual cells, creating ultimate scalability and deep cell insights. The Beacon platform* is ideally suited for cell line development, antibody discovery (including direct B-cell workflows), gene editing, and antibody engineering workflows. Each workflow provides a 100 fold increase in insights, 10 times faster, at a fraction of the cost.